Islam Makhachev will defend his lightweight belt for the third time on Saturday against iconic veteran contender Dustin Poirier in the main event of UFC 302: Makhachev vs. Poirier. Their five-round showdown will anchor the main UFC 302 fight card starting at 10 p.m. ET from the Prudential Center in Newark, New Jersey. It will be Makhachev's first title defense against a true lightweight. His previous two successful title defenses came against Alexander Volkanovski, the former featherweight champion who moved up a weight class in an effort to become a two-division champion. The No. 4-ranked Poirier is a two-time title challenger who has yet to capture the undisputed title. He earned another title bid on the strength of his upset of rising prospect Benoit Saint Denis in March.
Makhachev is a -625 favorite (risk $625 to win $100), while Poirier is a +450 underdog in the latest UFC 302: Makhachev vs. Poirier odds. In the co-main event, former middleweight champion Sean Strickland (-240) meets rugged brawler Paulo Costa (+200). Before locking in your picks for UFC 302: Makhachev vs. Poirier, make sure you see the MMA predictions and betting advice from SportsLine expert Daniel Vithlani.
From breaking down film and following fighters and their camps closely, to tracking sharp action and betting market signals, Vithlani covers the breadth of the MMA betting landscape top to bottom. He also trains amateur boxers and speaks regularly with MMA fighters to understand the sport's nuances.
Vithlani made his SportsLine debut in January 2023 and swept the main card for UFC 283 with a 5-0 record and has been a consistent winner ever since. Over the past 11 UFC pay-per-view events, Vithlani has gone 7-4 on main-event picks and his main-card selections in that span have netted his followers a profit of more than $1,200.
His highlights include calling an upset for Sean O'Malley (+210) against Aljamain Sterling (-250) at UFC 292 as part of a 4-1 main card and his UFC 299 winners included underdog selections on Poirier (+190) against Saint Denis (-230) and Michael Page (+110) against Kevin Holland (-130). Anyone who has followed him has seen massive returns.
Now, with UFC 302: Makhachev vs. Poirier on deck, Vithlani has studied the card from top to bottom and released his top selections. You can only see those picks at SportsLine.
UFC 302: Makhachev vs. Poirier preview
Makhachev (25-1) is currently No. 1 in the UFC's pound-for-pound fighter rankings. He hasn't lost in nearly nine years and brings a 13-fight winning streak into Saturday's UFC 302 main event. However, his star power thus far has been relatively limited for a fighter who appears to have the potential to be one of the promotion's more dominant champions in recent memory.
This is in large part because Makhachev keeps a modest public profile, but also has presented a somewhat abrasive disposition toward fellow fighters and media. Even so, even his most ardent critics can't deny that Makhachev has earned his status as an elite UFC champion.
The 32-year-old Dagestan native is a well-known prodigy of former undefeated lightweight champion Khabib Nurmagomedov, who is Makhachev's primary coach and mentor.
Makhachev is a heavy favorite against Poirier (30-8-1), the 11-year UFC veteran who is one of the most popular fighters on the UFC roster. Poirier's extensive resume includes two knockout wins over Conor McGregor, two wins over former featherweight champion Max Holloway and a 1-1 split with Justin Gaethje.
However, his two title challenges resulted in submission losses to Nurmagomedov and Charles Oliveira. Even so, his comeback win against the highly regarded prospect Saint Denis, who closed as greater than a 2/1 favorite, showed that the 35-year-old Louisiana native is still among the UFC's elite. You can see more UFC 302 picks at SportsLine.
Top UFC 302 predictions
We'll share one of Vithlani's UFC 302 selections here: He is siding with Alex Morono (-235) to get past Niko Price (+195) in a matchup of veteran welterweights.
Morono (24-9-1) is an eight-year UFC veteran who is known as a polished tactician in all aspects of MMA. He is also a successful and revered MMA coach when he's not training for his own fights. The 33-year-old Texan is coming off a decision win against Court McGee in April.
Price (15-7-2) is a seven-year UFC veteran who is a fan favorite because of his penchant for wild brawls that involve nonstop action from the opening bell. But the 34-year-old Florida native has just one win in his last four outings.
"Price's all-action style has taken its toll, and at this point he is just too hittable," Vithlani told SportsLine. You can see more UFC 302 picks at SportsLine.
How to make UFC 302 picks
Vithlani also has strong picks for Makhachev vs. Poirier and other bouts on the UFC 302 card. He's also backing a fighter who "has a granite chin and lethal body kicks" to emerge with a dominant victory. Those picks and analysis are only available at SportsLine.
Who wins UFC 302:Makhachev vs. Poirier, and how exactly does each fight end? Visit SportsLine now to get detailed picks on UFC 302, all from the MMA expert who profited more than $1,500 on his UFC main-card picks, and find out.
UFC 302 odds, fight card
See full UFC 302 picks, predictions, best bets here.
Islam Makhachev (-625) vs. Dustin Poirier (+450)
Sean Strickland (-240) vs. Paulo Costa (+200)
Kevin Holland (-260) vs. Michal Oleksiejczuk (+210)
Jailton Almeida (-260) vs. Alexandr Romanov (+210)
Randy Brown (-180) vs. Elizeu Zaleski dos Santos (+155)
Cesar Almeida (-120) vs. Roman Kopylov (+100)
Grant Dawson (-400) vs. Joe Solecki (+310)
Jake Matthews (-160) vs. Philip Rowe (+135)
Alex Morono (-240) vs. Niko Price (+200)
Bassil Hafez (-330) vs. Mickey Gall (+260)
Ailin Perez (-200) vs. Joselyne Edwards (+170)
Andre Lima (-250) vs. Mitch Raposo (+205)
